Novartis Research Scientist Interview Questions + Guide in 2025

Novartis is a global healthcare company dedicated to reimagining medicine to improve and extend patients' lives.

As a Research Scientist at Novartis, you will play a crucial role in advancing drug discovery and development, particularly in the areas of oncology and biotherapeutics. Your primary responsibilities will include designing and executing laboratory experiments, applying cell and molecular biology techniques for target validation, and collaborating with multidisciplinary teams. A strong foundation in in vitro cell-based assays, as well as hands-on experience with various laboratory techniques such as flow cytometry, Western blotting, and cell culture, is essential. You will also be expected to generate hypotheses, analyze data critically, and communicate findings effectively within and across teams. The ideal candidate will possess a collaborative mindset, exceptional organizational skills, and a genuine curiosity to expand their expertise in drug discovery optimization processes.

This guide will equip you with the insights and knowledge necessary to excel in your interview for the Research Scientist role at Novartis, enhancing your chances of securing a position in this esteemed organization.

The interview process for a Research Scientist at Novartis is designed to assess both technical expertise and cultural fit within the organization. It typically consists of several stages, each aimed at evaluating different aspects of a candidate's qualifications and potential contributions to the team.

1. Initial Screening

The process begins with an initial screening, which usually takes place via a phone call with a Human Resources (HR) representative. This conversation typically lasts about 30 minutes and focuses on your background, experience, and motivation for applying to Novartis. The HR representative will also provide insights into the company culture and the specific role, ensuring that you have a clear understanding of what to expect.

2. Technical Interviews

Following the initial screening, candidates often undergo one or more technical interviews. These interviews may be conducted virtually or in person and typically involve discussions with hiring managers or team members. During this stage, you can expect to be asked about your specific technical skills, including your experience with laboratory techniques relevant to the role, such as cell and molecular biology assays, in vitro experiments, and data analysis. You may also be required to solve work-related tasks or present your previous research findings to demonstrate your analytical and problem-solving abilities.

3. Panel Interview

Candidates who successfully navigate the technical interviews are usually invited to a panel interview. This stage involves meeting with multiple team members, including senior scientists and directors. The panel will assess your collaborative skills, ability to communicate findings, and how well you can work within a multidisciplinary team. Expect to discuss your approach to experimental design, troubleshooting, and how you handle challenges in a lab setting. This interview may also include behavioral questions to gauge your fit within the team and the broader Novartis culture.

4. Final Interview

In some cases, a final interview may be conducted with higher-level management or executives. This stage is less common but serves to ensure that candidates align with the strategic goals of the organization. It may involve discussions about your long-term career aspirations, contributions to the team, and how you envision your role within Novartis.

5. Follow-Up and Offer

After the interviews, candidates can expect a follow-up from HR regarding the outcome of their application. If selected, you will receive an offer that includes details about salary, benefits, and other employment terms.

As you prepare for your interview, it's essential to be ready for the specific questions that may arise during this process.

Here are some tips to help you excel in your interview.

Understand the Interview Structure

The interview process at Novartis can involve multiple stages, including phone interviews, panel interviews, and possibly a presentation. Be prepared for a full-day virtual or in-person interview with various team members, including hiring managers and directors. Familiarize yourself with the structure and be ready to engage with different interviewers, as they may have varying expectations and focus areas.

Prepare for Behavioral Questions

Expect to encounter behavioral questions that assess your problem-solving abilities and teamwork skills. Reflect on your past experiences and be ready to discuss specific situations where you demonstrated your ability to work collaboratively, troubleshoot issues, and adapt to changing circumstances. Use the STAR (Situation, Task, Action, Result) method to structure your responses clearly and effectively.

Showcase Your Technical Expertise

As a Research Scientist, you will be expected to have a strong foundation in cell and molecular biology techniques. Be prepared to discuss your hands-on experience with in vitro assays, data analysis, and experimental design. Highlight any specific techniques you are proficient in, such as flow cytometry, Western blotting, or cell culture, and be ready to explain how you have applied these skills in your previous roles.

Communicate Your Passion for Drug Discovery

Novartis values candidates who are not only technically skilled but also passionate about advancing drug discovery and improving patient outcomes. Be prepared to articulate why you are interested in this field and how your background aligns with Novartis's mission. Share any relevant experiences that demonstrate your commitment to research and innovation in biotherapeutics.

Emphasize Collaboration and Teamwork

Given the collaborative nature of the role, it’s essential to convey your ability to work effectively within multidisciplinary teams. Discuss instances where you have successfully collaborated with colleagues from different backgrounds or departments. Highlight your communication skills and your willingness to share knowledge and mentor others, as these traits are highly valued at Novartis.

Be Ready for Technical Problem-Solving Scenarios

You may be asked to design an experiment or troubleshoot a hypothetical scenario during the interview. Practice articulating your thought process clearly and logically. Be prepared to discuss how you would approach experimental design, data interpretation, and the steps you would take to address any challenges that arise.

Stay Informed About Novartis and Industry Trends

Demonstrating knowledge about Novartis's recent developments, research focus areas, and industry trends can set you apart from other candidates. Stay updated on the company’s pipeline, recent publications, and any news related to drug discovery and biotherapeutics. This knowledge will not only help you answer questions more effectively but also show your genuine interest in the company.

Follow Up with Gratitude

After the interview, send a thank-you email to express your appreciation for the opportunity to interview. Mention specific points from the conversation that resonated with you, reinforcing your interest in the role and the company. This small gesture can leave a positive impression and keep you top of mind as they make their decision.

By following these tips and preparing thoroughly, you can approach your interview with confidence and demonstrate that you are a strong fit for the Research Scientist role at Novartis. Good luck!

In this section, we’ll review the various interview questions that might be asked during a Research Scientist interview at Novartis. The interview process will likely focus on your technical expertise, problem-solving abilities, and collaborative skills, as well as your understanding of drug discovery and development processes. Be prepared to discuss your past experiences and how they relate to the responsibilities of the role.

Technical Skills

1. How would you design an experiment to test a new drug candidate's efficacy?

This question assesses your experimental design skills and understanding of drug discovery processes.

How to Answer

Discuss the steps you would take to formulate a hypothesis, select appropriate assays, and determine the metrics for success. Highlight your familiarity with in vitro and in vivo methodologies.

Example

“I would start by reviewing existing literature to identify potential mechanisms of action for the drug candidate. Then, I would design a series of in vitro assays to evaluate its efficacy against specific cancer cell lines, followed by in vivo studies in appropriate animal models to assess pharmacokinetics and therapeutic outcomes.”

2. Can you explain the significance of using cell-based assays in drug discovery?

This question evaluates your understanding of the role of cell-based assays in the drug development process.

How to Answer

Emphasize the importance of cell-based assays in providing insights into drug mechanisms, efficacy, and safety profiles.

Example

“Cell-based assays are crucial in drug discovery as they allow us to evaluate the biological activity of compounds in a controlled environment. They help in understanding the drug's mechanism of action and its effects on cellular pathways, which is essential for optimizing lead candidates.”

3. Describe your experience with molecular biology techniques. Which techniques are you most proficient in?

This question aims to gauge your hands-on experience with relevant laboratory techniques.

How to Answer

List the molecular biology techniques you have used, providing context on how you applied them in your previous roles.

Example

“I have extensive experience with techniques such as PCR, Western blotting, and flow cytometry. For instance, I used flow cytometry to analyze cell surface markers in a study aimed at characterizing immune responses to a novel therapeutic agent.”

4. How do you ensure the accuracy and reliability of your experimental data?

This question assesses your attention to detail and understanding of good laboratory practices.

How to Answer

Discuss the protocols you follow to maintain data integrity, including documentation practices and quality control measures.

Example

“I maintain meticulous records of all experiments in an electronic lab notebook, ensuring that all data is logged in real-time. I also implement regular calibration of equipment and participate in peer reviews of experimental protocols to ensure accuracy and reliability.”

5. Can you provide an example of a challenging problem you encountered in the lab and how you resolved it?

This question evaluates your problem-solving skills and resilience in a research setting.

How to Answer

Share a specific example that highlights your analytical thinking and ability to troubleshoot effectively.

Example

“During a project, I encountered inconsistent results in a cell viability assay. After reviewing the protocol, I realized that the cell culture conditions were not optimal. I adjusted the media composition and incubation times, which resolved the issue and led to reproducible results.”

Collaboration and Communication

1. Describe a time when you had to work collaboratively with a multidisciplinary team. What was your role?

This question assesses your teamwork and communication skills.

How to Answer

Highlight your ability to work with diverse teams and how you contributed to achieving a common goal.

Example

“I collaborated with chemists and biologists on a project aimed at developing a new drug conjugate. My role involved designing and executing biological assays to evaluate the efficacy of the conjugate, and I facilitated regular meetings to ensure alignment on project objectives.”

2. How do you communicate complex scientific concepts to non-scientific stakeholders?

This question evaluates your ability to convey information clearly and effectively.

How to Answer

Discuss your approach to simplifying complex information and ensuring understanding among diverse audiences.

Example

“I focus on using clear, jargon-free language and visual aids, such as graphs and charts, to illustrate key points. For instance, I presented our findings on a new therapeutic approach to the marketing team by using simplified diagrams to explain the mechanism of action.”

3. What strategies do you use to manage multiple projects simultaneously?

This question assesses your organizational skills and ability to prioritize tasks.

How to Answer

Share your methods for time management and project prioritization.

Example

“I use project management tools to track deadlines and progress across multiple projects. I prioritize tasks based on urgency and impact, and I regularly communicate with team members to ensure alignment and address any potential bottlenecks.”

4. How do you handle conflicts or disagreements within a team?

This question evaluates your conflict resolution skills and ability to maintain a positive team dynamic.

How to Answer

Discuss your approach to addressing conflicts constructively and fostering collaboration.

Example

“When conflicts arise, I believe in addressing them directly and respectfully. I encourage open dialogue to understand different perspectives and work towards a compromise that aligns with our project goals.”

5. What is your approach to mentoring junior team members?

This question assesses your leadership and mentoring abilities.

How to Answer

Share your philosophy on mentorship and how you support the development of others.

Example

“I believe in providing guidance through hands-on training and regular feedback. I encourage junior team members to ask questions and take ownership of their projects, which helps them build confidence and develop their skills.”