Exact Sciences Research Scientist Interview Questions + Guide in 2025

Exact Sciences is committed to transforming the way the world prevents, detects, and treats cancer, providing clarity to patients and clinicians when it matters most.

As a Research Scientist at Exact Sciences, you will play a pivotal role in the Research and Development department, taking on moderate to complex projects with limited guidance from senior scientists. Your responsibilities will encompass planning and executing experiments, analyzing data, and translating research concepts into viable diagnostic assay products. A strong foundation in molecular biology and biochemistry, along with experience in the medical device or biotech industries, is essential. You will be expected to communicate effectively, mentor junior staff, and contribute to a collaborative team environment that reflects Exact Sciences' commitment to innovation, integrity, and quality.

This guide will help you prepare for a job interview by equipping you with insights into the role, the company’s values, and the types of questions you may encounter, ultimately increasing your confidence and readiness.

The interview process for a Research Scientist position at Exact Sciences is designed to assess both technical expertise and cultural fit within the organization. The process typically unfolds in several structured stages:

1. Initial Phone Screening

The first step in the interview process is a 30-minute phone screening conducted by a recruiter. This conversation is generally friendly and informative, focusing on your background, motivations for applying, and understanding of the company’s mission. Expect questions that gauge your interest in Exact Sciences and your relevant experiences, particularly in laboratory settings.

2. Technical Interviews

Following the initial screening, candidates usually participate in a series of technical interviews. These interviews may be conducted virtually and typically involve discussions with lead scientists or team members. Each session lasts around 30 minutes and focuses on your technical knowledge, problem-solving abilities, and past research experiences. Be prepared to discuss specific projects you've worked on, your role in those projects, and how you approached challenges.

3. Behavioral Interviews

In addition to technical assessments, candidates will undergo behavioral interviews that often utilize the STAR (Situation, Task, Action, Result) format. These interviews aim to evaluate how your past experiences align with the company’s core values and culture. Expect to share examples of teamwork, conflict resolution, and instances where you demonstrated leadership or innovation in your work.

4. Onsite Interview (or Virtual Equivalent)

If you progress past the initial rounds, you may be invited for an onsite interview, which could also be conducted virtually depending on circumstances. This stage typically includes multiple interviews with various team members, allowing you to showcase your technical skills and collaborative abilities. You may also receive a tour of the facilities, providing insight into the work environment and culture at Exact Sciences.

5. Final Decision and Offer

After completing the interview rounds, candidates can expect a follow-up call regarding the outcome of their application. This call usually occurs within a week and may include an offer if you are selected for the position.

As you prepare for your interviews, consider the types of questions that may arise in each of these stages, particularly those that reflect your technical expertise and alignment with the company’s mission.

Here are some tips to help you excel in your interview.

Emphasize Your Passion for Cancer Research

Exact Sciences is dedicated to changing the landscape of cancer prevention and treatment. During your interview, convey your genuine passion for this mission. Be prepared to discuss why you want to work in cancer research specifically and how your personal values align with the company's goals. This will not only demonstrate your commitment but also show that you are a cultural fit for the organization.

Prepare for Behavioral Questions Using the STAR Method

Expect to encounter behavioral questions that assess how you handle various situations in the workplace. Use the STAR (Situation, Task, Action, Result) method to structure your responses. Think of specific examples from your past experiences that highlight your problem-solving skills, teamwork, and ability to learn from mistakes. Given the emphasis on company values, ensure your examples reflect those values in action.

Showcase Your Technical Expertise

As a Research Scientist, you will be expected to have a strong foundation in molecular biology, biochemistry, and relevant laboratory techniques. Be ready to discuss your technical skills in detail, including any specific methodologies you have used in previous roles. Highlight your experience with scientific instrumentation and your ability to analyze and interpret complex data. This will demonstrate your readiness to take on the technical challenges of the role.

Understand the Company’s Core Values

Exact Sciences places a strong emphasis on accountability, innovation, integrity, quality, and teamwork. Familiarize yourself with these values and think of examples from your past experiences that illustrate how you embody them. During the interview, weave these values into your responses to show that you not only understand the company culture but also actively contribute to it.

Be Ready for Collaborative Scenarios

Collaboration is key in a research environment. Be prepared to discuss your experiences working in teams, including your role, contributions, and how you navigated any challenges. Highlight your ability to communicate effectively with team members and your experience in leading projects or mentoring others. This will showcase your ability to thrive in a collaborative setting, which is essential for success at Exact Sciences.

Ask Insightful Questions

At the end of your interview, you will likely have the opportunity to ask questions. Use this time to demonstrate your interest in the company and the role. Inquire about ongoing projects, the team dynamics, or how the company measures success in research initiatives. Thoughtful questions not only show your enthusiasm but also help you assess if the company is the right fit for you.

Follow Up Professionally

After your interview, send a thank-you email to express your appreciation for the opportunity to interview. Reiterate your interest in the position and briefly mention a key point from your conversation that resonated with you. This not only reinforces your enthusiasm but also keeps you top of mind as they make their decision.

By following these tips, you will be well-prepared to make a strong impression during your interview at Exact Sciences. Good luck!

In this section, we’ll review the various interview questions that might be asked during a Research Scientist interview at Exact Sciences. The interview process will likely focus on your technical expertise, problem-solving abilities, and alignment with the company's mission to combat cancer. Be prepared to discuss your experiences in the lab, your understanding of relevant scientific principles, and how you can contribute to the team.

Experience and Background

1. Why do you want to work at Exact Sciences?

This question assesses your motivation and alignment with the company's mission.

How to Answer

Express your passion for cancer research and how Exact Sciences' goals resonate with your personal and professional values. Highlight any specific projects or initiatives of the company that inspire you.

Example

“I am deeply motivated by the opportunity to contribute to innovative cancer diagnostics. Exact Sciences’ commitment to improving patient outcomes through advanced technology aligns perfectly with my career aspirations and personal values.”

2. Tell me about your experience in the lab.

This question evaluates your hands-on experience and technical skills.

How to Answer

Discuss specific techniques you have mastered, the types of experiments you have conducted, and any relevant projects you have worked on. Emphasize your ability to work independently and collaboratively.

Example

“In my previous role, I conducted experiments involving PCR and next-generation sequencing. I collaborated with a team to develop a diagnostic assay, where I was responsible for optimizing protocols and analyzing data, which led to a significant improvement in assay sensitivity.”

3. Describe a time you worked with a team. What was your role?

This question gauges your teamwork and collaboration skills.

How to Answer

Use the STAR method to describe a specific situation where you contributed to a team project. Highlight your role, the challenges faced, and the outcome.

Example

“I was part of a multidisciplinary team tasked with developing a new diagnostic tool. As the technical lead, I coordinated the experimental design and ensured effective communication among team members, which resulted in the successful launch of the product ahead of schedule.”

4. Name a time you were wrong in the workplace and how did you handle it.

This question tests your ability to learn from mistakes and demonstrate accountability.

How to Answer

Share a specific instance where you made an error, how you addressed it, and what you learned from the experience. Emphasize your commitment to continuous improvement.

Example

“During a project, I miscalculated the sample sizes needed for our experiments, which delayed our timeline. I immediately informed my supervisor, recalibrated our approach, and implemented a more rigorous review process for future calculations to prevent similar issues.”

5. Why are you motivated to fight against cancer?

This question seeks to understand your personal connection to the field.

How to Answer

Share any personal experiences or professional motivations that drive your passion for cancer research. Connect your motivations to the work being done at Exact Sciences.

Example

“Having lost a family member to cancer, I have a personal stake in this fight. I am motivated to contribute to research that can lead to earlier detection and better treatment options, ultimately improving patient outcomes.”

Technical Skills and Knowledge

1. What molecular biology techniques are you proficient in?

This question assesses your technical expertise in relevant methodologies.

How to Answer

List the specific techniques you have experience with, and provide context on how you have applied them in your work.

Example

“I am proficient in techniques such as PCR, gel electrophoresis, and CRISPR gene editing. In my last project, I utilized PCR to amplify target genes for sequencing, which was crucial for our diagnostic assay development.”

2. How do you ensure compliance with GMP and ISO standards in your work?

This question evaluates your understanding of regulatory requirements.

How to Answer

Discuss your familiarity with GMP and ISO standards and how you incorporate these practices into your daily work.

Example

“I ensure compliance by maintaining meticulous lab notebooks, following established protocols, and conducting regular audits of our processes. I also stay updated on regulatory changes to ensure our practices meet the latest standards.”

3. Can you explain a complex scientific concept to a non-scientific audience?

This question tests your communication skills and ability to simplify complex information.

How to Answer

Choose a scientific concept you are comfortable with and explain it in layman's terms, demonstrating your ability to communicate effectively.

Example

“I can explain next-generation sequencing as a way to read the genetic code of an organism. It’s like reading a book where each letter represents a part of the DNA, helping us understand genetic variations that can lead to diseases.”

4. Describe your experience with statistical software and data analysis.

This question assesses your analytical skills and familiarity with data interpretation.

How to Answer

Mention the statistical software you have used, the types of analyses you performed, and how the results impacted your projects.

Example

“I have experience using JMP for statistical analysis, where I performed regression analyses to identify significant predictors in our experimental data. This analysis was crucial in refining our diagnostic assay’s performance metrics.”

5. How do you approach troubleshooting in the lab?

This question evaluates your problem-solving skills and critical thinking.

How to Answer

Describe your systematic approach to identifying and resolving issues in the lab, emphasizing your analytical skills.

Example

“When troubleshooting, I first review the experimental design and protocols to identify potential sources of error. I then analyze the data step-by-step, consulting with colleagues if needed, to pinpoint the issue and implement corrective actions.”