Prepare for and practice interview questions from Charles River Laboratories.

Charles River Laboratories Interview Questions

A/B Testing

Algorithms

Analytics

Machine Learning

Probability

Product Metrics

Python

Statistics

Charles River Laboratories Interview Guides

Suppose there exists a new airline named Jetco that flies domestically across North America. Jetco recently had a study commissioned that tested the boarding time of every airline, and it came out that Jetco had the fastest average boarding times of any airline.

What factors could have biased this result, and what would you look into?

What could potentially bias the average boarding time in favor of an airline that only flies domestically?

What could potentially bias the average boarding time in favor of an airline that only flies domestically?

Boarding Times Bias

A new airline came out as the fastest average boarding times compared to other airlines.  What factors could have biased this result and what would you look into?

You are testing hundreds of hypotheses with many t-tests. What considerations should be made?

What is a key disadvantage of the F-test when compared to multiple t-tests?

What is a key disadvantage of the F-test when compared to multiple t-tests?

Hundreds of Hypotheses

You are testing hundreds of hypotheses with many t-tests. What considerations should be made?

In an A/B test, how can you check if assignment to the various buckets was truly random?

In an A/B test, which of the following is a common method to determine if the assignment to the test groups was truly random?

In an A/B test, which of the following is a common method to determine if the assignment to the test groups was truly random?

Random Bucketing

A/B Testing & Experimentation

Charles River Laboratories Salaries by Position

This job is with Charles River, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
Job Summary A Research Analyst II supports the receipt, login, distribution, and disposal of materials utilizingthe appropriate software systems. Staff manages reagents, test materials, matrices, regulated
and non-regulated samples, and laboratory consumables. Staff also supports all disciplines bystoring, distributing, and archiving regulated and non-regulated samples and study material within the appropriate software systems. Staff are also knowledgeable in the application of GxP's and applicable SOPs, along with adhering to study protocols to accurately receive, store and dispose of laboratory materials.

Essential Duties and Responsibilities
• Efficiently perform and document all procedures, materials and results in compliance with applicable regulatory standards as applicable (protocols, methods, SOPs, etc.)
• Independently maintains disposition of study specific materials
• Assist with laboratory support functions such as labeling/verification and receiving/login supplies
• Assist with maintaining study specific inventory consumables with minimal oversight
• Demonstrate effective communication skills through informal discussions with peers, supervisor, and team
• Manage receipt and maintenance of test (or archiving) materials and laboratory consumables
• Participate in process improvement initiatives with minimal oversight
• Monitor laboratory (or archiving) storage units for compliance with SOPs/protocols
• Ensure laboratory waste is properly disposed of to designated areas
• Assist in the completion of laboratory investigations, assay troubleshooting and quality observations with minimal oversight
• Perform verification of receipt records for accuracy and compliance with SOPs and protocol
• Independently execute proper receipt of test (or archiving) materials
• Independently prepares domestic shipments
• Independently manage international shipments
• Oversee and maintain responsibility for specific functional area with minimal oversight
• Perform clinical and non-clinical sample disposition and archive with oversight as needed
• Perform verification of shipments with oversight as needed

Job Description:
• Perform verification of clinical receipt records for accuracy and compliance to SOPs and study plans
• Operate specialized equipment (e.g. BSC, Nitrogen Atmosphere Glovebox) with minimal oversight as needed
• Perform log in, storage and aliquoting of Controlled Compounds as required by operational area with minimal oversight
• Perform all other related duties as assigned

Job Qualifications Education: HS/GED/Associate's degree or equivalent with a minimum of 3 years of relevant experience. Bachelor's degree (BA/BS) in a relevant field with 1-2 years work experience
Experience: An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
Certification/Licensure: None

Other:
• Ability to communicate verbally and in writing at all levels inside and outside the organization
• Basic familiarity with Microsoft Office Suite
• Computer skills, commensurate with Essential Functions, including the ability to learn a validated system
• Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts, sometimes on short notice
• Ability to work under specific time constraints

The pay for this position is $24.00/hr. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment Opportunity
Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.
230875

This job is with Charles River, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
Job Summary We are seeking a Research Analyst I (Bioanalytical Chemistry) for our Safety Assessment Group site located in Ashland, Ohio.
Generate and record data with minimal supervision in the performance of studies. Responsible for handling and processing samples and performing accurate data collection and reporting. Perform laboratory tasks by various basic methods.

Perform basic laboratory procedures and collect and record/document research data in compliance with Good Laboratory Practices (GLPs), Standard Operating Procedures (SOPs), study protocols and company policies/practices.
Under supervision may act as lead/primary technician on basic studies.
Basic Understand/Knowledge LCMS
Input, print and edit computer entries (e.g., laboratory data).
Prepare materials and data for shipment and archiving.
Receive samples and complete tracking documentation.
Review documentation of functions performed as part of quality control requirements.
Perform study preparation activities including collection tube labeling and room setup.
Maintain clean work areas.
Perform all other related duties as assigned.

The following are miminum requirements related to the Research Assistant I position.
Education: Bachelor's degree (B.A. / B.S) or equivalent in laboratory science or related discipline required.
Experience: Zero to two years related experience in biology, chemistry/pharmacy, or similar lab environment GLP experience preferred.
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Certification/Licensure: None
Other: Proficient in basic technical skills and the operation of data collection equipment. Knowledge of GLPs and other federal regulations and guidelines. Basic understanding of study design and protocols; able to read basic study protocols and extract pertinent information. Must be able to perform effectively as a team member, accurately record data, follow verbal and written instructions, communicate effectively, and interact in a professional manner with management, coworkers, and sponsors. Able to quickly learn and utilize computer programs as needed; previous computer experiences preferred.
The pay range for this position is $21.00 per hour. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.
231030

This job is with Charles River, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
Job Summary Charles River Laboratories (CRL) is seeking a research analyst to join our integrated toxicology (ITox) team at the Kansas City site. This site is the first of its kind, bridging CRL's Discovery and Safety Assessment business units, while bringing automation to standard lead optimization toxicology study models to deliver rapid study results to our clients. When you join our team, you will have a significant impact on the health and well-being of people across the globe. As a Research Analyst, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
From test article receipt to disposition, the Formulations team works with internal customers and clients providing logistical resources to produce reproducible formulations, investigating/troubleshooting where necessary to achieve a time-oriented, quality formulation bound by protocol and standard operating procedure requirements. The research analyst is proficient in the setup and execution of formulations, under supervision and learning to perform skills independently. Additionally, the research analyst will work towards supporting the site through cross training and working cross functionally as workload allows outside of the lab.

ESSENTIAL DUTIES AND RESPONSIBILITIES:
Calculate required vehicle and test article amounts based on study criteria for preparations.
Work towards independently generating, verifying, and/or reviewing instructions, and other study data as needed, based on body weights, days of dosing, etc.
Ability to follow detailed protocols and other reference materials to generate instructions for preparation and sampling of formulated test materials.
Apply laboratory experience to participate in troubleshooting.
Demonstrates effective communication skills through formal discussions.
Actively participate in laboratory development and process improvement initiatives.
Recognize Formulation and/or data issues and communicate those issues to the Study Director and Management.
Verify and/or review shipments and formulation procedures to ensure quality and completeness.
Identify potential scientific issues and develop solutions.
Execution of formulation instructions and preparation procedures.
Effectively direct junior technical staff in the execution of formulation instructions and preparation procedures.
Assist to sterilize laboratory equipment using autoclave or other methods
Assist in washing and maintenance of glassware and lab cleanliness
Consult with Sponsor representatives and Principal Investigators/Study Directors on appropriate formulation methods for assigned compounds.
Participate in scientific discussions with internal and external customers.
Participate in laboratory investigations, providing scientific input and direction, as needed.
Participate in the development of procedures for formulation of test articles and compounds in vehicle components for dosing.
Be responsible for the disposal and transport of residual dosing material, non-regulated pharmaceutical solids, accumulated single-use containers to designated waste receiving areas
Demonstrate effective communication skills through informal discussions with peers, management, and team
Cross functionally train and execute on learned/honed skills outside of the Formulations Lab to support the overall pulse of the workload as we embrace a one team culture.
Performs all other related duties as assigned.

Job Qualifications Education:
Bachelor's degree (B.A./B.S.), or equivalent,in a scientific related discipline.

Experience:
One year in a relevant field, preferably a pharmaceutical, chemistry, or contract research laboratory.
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Certification/Licensure:None.
Excellent written and verbal communication skills.
Ability to manage multiple tasks and priorities to achieve goals.
Computer skills (e.g., Microsoft Office Suite), commensurate with essential functions, including the ability to learn a validated system.
Ability to ensure that a safe working environment is maintained by observing all safety procedures and working methods by making proper use of protective clothing and equipment, and by reading, understanding, and following all safety documents issued or notified of.
Ability to ensuretheintegrityof the studies and fulfill the requirements by performing the activitiesaccordingto the Business Operating Procedures (BOP) and theInstitutionalAnimal Care and UseCommittee(IACUC)rules.
Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts, sometimes on short notice.
Ability to work under specific time constraints.

PHYSICAL DEMANDS:
Must be able to lift, move, manipulate and/or hold heavy objects up to and including 50 pounds; this includes work materials, equipment, and/or supplies.
Must be able to perform procedures, standing or sitting, for long periods of time, using appropriate instruments, reaching with hands and arms, working in narrow spaces, and wearing safety equipment (PPE) according to OSHA regulations and company standards.
Must be able to frequently hold and manipulate work materials while utilizing fine motor skills.
Must be able to regularly provide information to and receive information from/through various technologies, media, sources, and contacts. Must be able to accurately exchange information in these situations.
Regularly operates a computer and other office productivity machinery, such as a calculator, copy machine, and computer printer.
Move about inside the work area to access file cabinets, office machinery, etc.
Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.

WORK ENVIRONMENT:
General office and lab working conditions, the noise level in the work environment is usually moderate.
While performing the duties of this job the employee is regularly required to wear protective clothing (i.e., goggles, face shield, cap, gloves, scrubs, shoe covers), work near toxic or caustic chemicals, work with biohazards.
The employee may occasionally be exposed to live animals with risk of exposure to allergens, zoonotic disease, and biohazards.
The employee may occasionally be exposed to fumes or airborne particles, unpleasant odors, and extreme temperature conditions.
The noise level in the work environment ranges from moderate to high depending upon the task being performed.

The pay rate for this role is $23.50/hour.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.
230475

This job is with Charles River, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
Job Summary We are seeking anexperienced ResearchScientist (Bioanalytical) for ourSafety Assessmentsite located inReno, NV.
Serve as a scientist in the conduct of assigned preclinical and clinical research studies of basic to moderate complexity, to include study management, interpretation and reporting of study data, and assuring the regulatory compliance of these projects.

We are seeking a Research Scientist I (Bioanalytical) for ourSafety Assessmentsite located inReno, NV.
This position will serve as a scientist in the conduct of assigned nonclinical and clinical bioanalytical studies at all levels of complexity, to include study management, interpretation and reporting of study data, and assuring the regulatory compliance of these projects, as appropriate. Additional responsibilities include serving as a primary scientific contact for key clients and the on-site support of their programs, as well as the support of specialty studies. The ideal candidate will have experience with design and optimization of ligand binding assays including ELISA, MSD, or Gyrolab platforms.
• Bachelor's degree (B.S./B.A.) or equivalent in a scientific related discipline. Related Master's degree (M.S./M.A.) or PhD preferred.
• Minimum of 3 to 5 years related experience in the contract research, academic, or pharmaceutical industry.
• An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
• Understanding of regulatory requirements of study types assigned, as well as Testing Facility SOPs and the Good Laboratory Practices (GLPs), as appropriate.
• Effective written and verbal communication skills.
• Ability to handle multiple projects, prioritize work and meet deadlines.
• Proficiency in the use of standard software including Microsoft® Excel, Word, Powerpoint, etc. and with standard laboratory calculations.

The pay range for this position is $90,000 to $95,000 annually USD. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.

Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.
229506

Question	Topic	Difficulty	Ask Chance
Boarding Times Bias	Statistics	Medium	Very High
Hundreds of Hypotheses	Statistics	Medium	Very High
Random Bucketing	A/B Testing & Experimentation	Medium	Very High

Charles River Laboratories Interview Questions

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Charles River Laboratories Interview Questions

Charles River Laboratories Salaries by Position

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