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Thermo Fisher Scientific Interview Questions

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Machine Learning

RMS Error

Missing Housing Data

What are the logistic and softmax functions? What is the difference between the two?

Softmax vs Logistic

Decision Tree Evaluation

How to model merchant acquisition in a new market?

Merchant Acquisition

Data Structures & Algorithms

Moving Window

Given a json string with nested objects, write a function that flattens all the objects to a single key-value dictionary.

Flatten JSON

Given an array and a target integer, write a function that returns the indices of two integers in the array that add up to the target integer.

Target Indices

Given a list of strings, write a function that returns the longest common prefix

Common Prefix

Valid Anagram

Select the 2nd highest salary in the engineering department

2nd Highest Salary

Last Transaction

Cumulative Distribution

Given a users table, write a query to get the cumulative number of new users added by the day, with the total reset every month. 

Cumulative Reset

Duplicate Rows

Analytics

How would you analyze the dataset to understand exactly where the revenue loss is occurring?

Evaluating Revenue Decline

Describing a data project and its challenges

Hurdles In Data Projects

Strategically resolving misaligned expectations with stakeholders for a successful project outcome

Stakeholder Communication

How to present complex data insights with clarity and adaptability tailored to a specific audience

Presentations and Insights

Making data-driven insights actionable for those without technical expertise

Simple Explanations

Statistics

P-value to a Layman

Reducing Error Margin

Unbiased Estimator

Describe linear regression to various audiences with different levels of knowledge.

Explaining Linear Regression to Different Audiences

What is the difference between Logistic and Linear Regression?

Linear vs Logistic Regression

When an interviewer asks a question along the lines of:

<ul>
<li>What would your current manager say about you? What constructive criticisms might he give?</li>
<li>What are your three biggest strengths and weaknesses you have identified in yourself?</li>
</ul>

How would you respond?

When asked about your strengths in an interview, what is an effective way to respond?

When asked about your strengths in an interview, what is an effective way to respond?

Your Strengths and Weaknesses I

Which of the following is an acceptable strategy when discussing weaknesses in an interview?

Which of the following is an acceptable strategy when discussing weaknesses in an interview?

Your Strengths and Weaknesses II

What do you tell an interviewer when they ask you what your strengths and weaknesses are?

Your Strengths and Weaknesses

Brainteasers

When an interviewer asks you a question along the lines of:

<ul>
<li>Why did you apply to our company?</li>
<li>What are you looking for in your next job?</li>
<li>What makes you a good fit for our company?</li>
</ul>

How should you respond?

When asked 'What are you looking for in your next job?' in an interview, how can you tie the company's employee benefits into your response?

When asked 'What are you looking for in your next job?' in an interview, how can you tie the company's employee benefits into your response?

Why Do You Want to Work With Us I

How can company values be used effectively in an interview when asked 'What makes you a good fit for our company?'

How can company values be used effectively in an interview when asked 'What makes you a good fit for our company?'

Why Do You Want to Work With Us II

When responding to the question 'Why did you apply to our company?' during an interview, what aspect should you highlight?

When responding to the question 'Why did you apply to our company?' during an interview, what aspect should you highlight?

Why Do You Want to Work With Us III

How would you answer when an Interviewer asks why you applied to their company?

Why Do You Want to Work With Us

How would you explain what a p-value is to someone who is not technical?

What does a p-value in a statistical test represent?

What does a p-value in a statistical test represent?

P-value to a Layman I

In a statistical test, how does a low p-value (less than 0.05) influence our decision about the null hypothesis?

In a statistical test, how does a low p-value (less than 0.05) influence our decision about the null hypothesis?

P-value to a Layman II

Describe a data project you worked on. What were some of the challenges you faced?

Given a string, write a function to determine if it is palindrome or not.

Note: A palindrome is a word/string that is read the same way forward as it is backward, e.g. <code>&#39;reviver&#39;</code>, <code>&#39;madam&#39;</code>, <code>&#39;deified&#39;</code> and <code>&#39;civic&#39;</code> are all palindromes, while <code>&#39;tree&#39;</code>, <code>&#39;music&#39;</code> and <code>&#39;person&#39;</code> are not palindromes.

Example:

Input:

<pre tabindex="0" class="chroma"><code>word1 = &#34;tree&#34;
word2 = &#34;radar&#34;
</code></pre>

Output:

<pre tabindex="0" class="chroma"><code>def is_palindrome(word1) -&gt; False
def is_palindrome(word2) -&gt; True
</code></pre>

Given a string, write a function to determine if it is palindrome or not.

String Palindromes

Let’s say that you’re training a classification model.

How would you combat overfitting when building tree-based models?

Let's say that you're training a classification model.   How would you combat overfitting when building tree-based models?

Overfit Avoidance

How would you handle the data preparation for building a machine learning model using imbalanced data?

Addressing imbalanced data in machine learning through carefully prepared techniques.

Data Preparation for Imbalanced Data

Talk about a time when you had trouble communicating with stakeholders. How were you able to overcome it?

Write a SQL query to select the 2nd highest salary in the engineering department.

Note: If more than one person shares the highest salary, the query should select the next highest salary.

Example:

Input:

<code>employees</code> table

<table>
<thead>
<tr>
<th>Column</th>
<th>Type</th>
</tr>
</thead>

<tbody>
<tr>
<td><code>id</code></td>
<td>INTEGER</td>
</tr>

<tr>
<td><code>first_name</code></td>
<td>VARCHAR</td>
</tr>

<tr>
<td><code>last_name</code></td>
<td>VARCHAR</td>
</tr>

<tr>
<td><code>salary</code></td>
<td>INTEGER</td>
</tr>

<tr>
<td><code>department_id</code></td>
<td>INTEGER</td>
</tr>
</tbody>
</table>
<code>departments</code> table

<table>
<thead>
<tr>
<th>Column</th>
<th>Type</th>
</tr>
</thead>

<tbody>
<tr>
<td><code>id</code></td>
<td>INTEGER</td>
</tr>

<tr>
<td><code>name</code></td>
<td>VARCHAR</td>
</tr>
</tbody>
</table>
Output:

<table>
<thead>
<tr>
<th>Column</th>
<th>Type</th>
</tr>
</thead>

<tbody>
<tr>
<td><code>salary</code></td>
<td>INTEGER</td>
</tr>
</tbody>
</table>

Explain the difference between the XGBoost and random forest algorithms and give an example where you would use one over the other.

Why might a data scientist choose to use XGBoost instead of Random Forest for a particular machine learning task?

Why might a data scientist choose to use XGBoost instead of Random Forest for a particular machine learning task?

XGBoost vs Random Forest: Choice

Xgboost vs Random Forest

How does random forest generate the forest? Additionally, why would we use it over other algorithms such as logistic regression?

What happens when you average the output on multiple decision trees?

What happens when you average the output on multiple decision trees?

Average Trees

Random Forest Explanation

What is the difference between Logistic and Linear Regression?

When would use one instead of the other in practice?

Tell me about a project in which you had to clean and organize a large dataset.

Describing a real-world data cleaning and organization project

Data Cleaning Experiences

Data Pipelines

Let’s say we want to launch a re-design of a landing page to improve the click-through rate. We can do this by implementing an AB test.
Given that we launch an AB test, how would you infer if the results of the click-through rate were statistically significant or not?

How can you accurately conclude if the results of an A/B test, conducted to evaluate the effectiveness of a landing page redesign, are statistically significant?

How can you accurately conclude if the results of an A/B test, conducted to evaluate the effectiveness of a landing page redesign, are statistically significant?

Statistically Significant Test

Precisely ascertain whether the outcomes of an A/B test, executed to assess the impact of a landing page redesign, exhibit statistical significance.

A/B Testing

What are the key differences between classification models and regression models?

What is the MOST important difference between regression and classification models?

What is the MOST important difference between regression and classification models?

Classification vs Regression

Classification and Regression

Given an array and a target integer, write a function <code>sum_pair_indices</code> that returns the indices of two integers in the array that add up to the target integer. If not found, just return an empty list.

Note: Can you do it on $O(n)$ time?

Note: Even though there could be many solutions, only one needs to be returned.

Example 1:

Input:

<pre tabindex="0" class="chroma"><code>array = [1 2 3 4] 
target = 5 
</code></pre>

Output:

<pre tabindex="0" class="chroma"><code>def sum_pair_indices(array, target) -&gt; [0 3] or [1 2]
</code></pre>

Example 2:

Input:

<pre tabindex="0" class="chroma"><code>array = [3]
target = 6 
</code></pre>

Output:

<pre tabindex="0" class="chroma"><code>Do NOT return [0 0] as you can&#39;t use an index twice.
</code></pre>

Regularization and cross-validation are two common techniques used to improve the performance of machine learning algorithms.

When should you use one versus the other?

Given the choices below, which one is an example of a scenario where we should be using regularization?

Given the choices below, which one is an example of a scenario where we should be using regularization?

Regularization Example

Regularization and Validation

How would you convey insights and the methods you use to a non-technical audience?

What’s the relationship between PCA and K-means clustering?

What does the variable “k” in k-means clustering refer to?

What does the variable "k" in k-means clustering refer to?

Input of K-means

PCA and K-Means

Let’s say you work as a data scientist at a bank.

You are tasked with building a decision tree model to predict if a borrower will pay back a personal loan they are taking out.

<ol>
<li>How would you evaluate whether using a decision tree algorithm is the correct model for the problem?</li>

<li>Let’s say you move forward with the decision tree model. How would you evaluate the performance of the model before deployment and after?</li>
</ol>

Describe a time when you had to define a long-term vision for a project or team and move it from concept to reality.

Interviews for leadership or senior technical roles look for more than just “finishing a project.” Your answer should specifically address:

<ol>
<li>The “Why”: What data or organizational gap necessitated this vision?</li>
<li>The Framework: How did you translate a high-level goal into a roadmap?</li>
<li>The Friction: How did you handle stakeholders or team members who were skeptical of the new direction?</li>
</ol>

Vision Setting and Execution Strategy

Business Case

Given a <code>users</code> table, write a query to return only its duplicate rows.

Example:

Input:

<code>users</code> table

<table>
<thead>
<tr>
<th>Column</th>
<th>Type</th>
</tr>
</thead>

<tbody>
<tr>
<td><code>id</code></td>
<td>INTEGER</td>
</tr>

<tr>
<td><code>name</code></td>
<td>VARCHAR</td>
</tr>

<tr>
<td><code>created_at</code></td>
<td>DATETIME</td>
</tr>
</tbody>
</table>

We want to build a model to predict housing prices in the city of Seattle. We’ve scraped 100K sold listings over the past three years but found that around 20% of the listings are missing square footage data.

How do we deal with the missing data to construct our model?

We want to build a model to predict housing prices in the city of Seattle. We’ve scraped 100K sold listings over the past three years, but have discovered that around 20% of the listings are missing square footage data.

How would you approach dealing with this missing data, in order to construct the most useful predictive model possible?

We want to build a model to predict housing prices in the city of Seattle. We’ve scraped 100K sold listings over the past three years, but have discovered that around 20% of the listings are missing square footage data.

How would you approach dealing with this missing data, in order to construct the most useful predictive model possible?



Given two strings, write a function to return <code>True</code> if the strings are anagrams of each other and <code>False</code> if they are not.

Note: A word is not an anagram of itself.

Example 1:

Input:

<pre tabindex="0" class="chroma"><code>string_1 = &#34;listen&#34;
string_2 = &#34;silent&#34;
</code></pre>

Output:

<pre tabindex="0" class="chroma"><code>True
</code></pre>

Example 2:

Input:

<pre tabindex="0" class="chroma"><code>string_1 = &#34;banana&#34;
string_2 = &#34;bandana&#34;
</code></pre>

Output:

<pre tabindex="0" class="chroma"><code>False
</code></pre>

How would you explain the concept of linear regression to three different audiences: a child, a first-year college student, and a seasoned mathematician? Ensure your explanations are tailored to the understanding level of each audience.

An ecommerce company is experiencing a reduction in revenue for the past 12 months. You have the following transaction data:

<ul>
<li>Date of sale</li>

<li>Total $ Amount paid by customer</li>

<li>Profit Margin per unit</li>

<li>Quantity of item</li>

<li>Item category</li>

<li>Item subcategory</li>

<li>Marketing attribution source</li>

<li>% discount applied</li>
</ul>

How would you analyze the dataset to understand exactly where the revenue loss is occurring?

Let’s say you’re interning at a fintech startup that’s building a platform for online games of chance. During testing, one of your simulations flips a coin 10 times and gets 8 tails and 2 heads.

How would you determine if the coin is fair, and what statistical approach would you use to support your conclusion?

How would you assess if a coin is fair after observing 8 tails in 10 flips?

Fair Coin

Probability

How comfortable are you presenting your insights?

What are the logistic and softmax functions? What is the difference between the two?

What makes them useful for use in logistic regression?

In logistic regression, how is the predicted class determined based on the logistic function?

In logistic regression, how is the predicted class determined based on the logistic function?

Softmax vs Logistic II

What is the key characteristic of the logistic function that makes it useful for mapping continuous values to a probability?

What is the key characteristic of the logistic function that makes it useful for mapping continuous values to a probability?

Softmax vs Logistic I

Let’s say that you’re a data scientist at DoorDash.

How would you build a model to predict which merchants the company should go after for acquisition when entering a new market?

Calculate Moving Average	SQL	Easy
Predict Customer Churn	Machine Learning	Medium
A/B Test Significance	Statistics	Medium
Optimize Query Performance	SQL	Hard
Feature Importance Analysis	Machine Learning	Medium
Clean Missing Data	Python	Easy
Neural Network Architecture	Deep Learning	Hard
Calculate Cohort Retention	SQL	Medium
Bayesian Probability	Statistics	Easy
Recommend Similar Products	Machine Learning	Hard

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