About the roleThe Preclinical Safety group in NIBR is engaged in all phases of drug discovery and development and plays a critical role in moving these breakthroughs into patients. You will be part of a team conducting the postmortem (ex vivo) aspects of preclinical safety studies in various laboratory animal species (mainly rats and mice). Your work will support the broad Novartis portfolio including oncology, immunology, neuroscience, cardiovascular, renal and metabolic disease with diverse technology platform including chemistry, biotherapeutics, RNAs, cell and gene therapy and radioligand therapy. You will be key to help bring these innovative medicines to patients. As such you will work closely with a group of curious and energized scientists. You will be joining a larger group which offer many opportunities for growth and development in other areas of preclinical and investigative safety including cross training to execute the in vivo aspects of preclinical studies, molecular pathology techniques, digital pathology, image analysis and electron microscopy. Your key responsibilities will include: -Planning and conduct of full rodent necropsy and histology procedures. -Investigative studies that include other cutting edge activities might be conducted including tissue collection and preparation for molecular pathology and transmission/scanning electron microscopy. -Scanning slides for digital pathology analysis -Participating in study planning meetings -Arrange sample containers for necropsy and histology slides EEO Statement We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message: <ul> <li>Novartis: e-mail us.reasonableaccommodations@novartis.com or call +1 (877)395-2339 </li><li>Sandoz: e-mail reasonable.accommodations@sandoz.com or call: +1-609-422-4098</li></ul>Role RequirementsEssential Requirements: AS/AAS degree in life sciences with a minimum of 3 years of relevant experience with necropsy and/or histology; BS/BA degree preferred. * Computer skills in Office software. Desirable: * AALAS, HT, MT, MSA, Medical Technologist/Scientist (ASCP), or Medical Laboratory Technician (ASCP) certifications. Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You'll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $80,000 and $120,000/year ; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

393017BRResearch Scientist II, R&DUSAAbout the rolePosition is on-site in San Diego, CA#LI-OnsiteAbout the role:The Biologics Research Center (BRC) Cell & Gene Therapy unit at Novartis Biomedical Research in San Diego, California is seeking a motivated Research Scientist II to contribute in early-stage recombinant adeno-associated virus (AAV) gene therapy portfolio. BRC is an innovative hub focuses on building new modalities that tackle complex biology and enable the creation of advanced biotherapeutics, siRNAs and cell & gene therapies to improve patients' lives. In collaboration within BRC and with Disease Areas, the Cell & Gene Therapy unit brings viral engineering in AAV gene therapy to create transformative medicine.The prospective Research Scientist will support early-stage AAV gene therapy pipeline portfolio focusing on downstream manufacture developability of novel AAV capsids, executing early-stage downstream method exploration and building improved process technologies for AAV manufacture.Your Key Responsibilities:Your responsibilities include, but are not limited to:* Perform different scales of purification process including depth filtration, ultracentrifugation, AKTA column chromatography, and TFF unit operations for manufacturing of AVV gene therapy vectors across multiple early-stage programs and disease areas to ensure on time delivery.* Execute experiments to drive innovative technology and platform evaluation for next generation capsids.* Perform experiment-related activities including buffer preparation, equipment maintenance, sample labelling and analytical sample submissions.* Work collaboratively with upstream process development and analytical development teams.* Engage collaboratively in operational and scientific discussion within internal team* Assist knowledge transfer and work collaboratively with Technical Research & Development team to advance pipeline programs into clinical phases.* Prepare protocols, reports, and provide high quality data and electronic notebook documentation.* Other related duties as assigned.This position will be located at the San Diego, CA site and will not have the ability to be located remotely.EEO StatementWe are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:Novartis: e-mail us.reasonableaccommodations@novartis.com or call +1 (877)395-2339Sandoz: e-mail reasonable.accommodations@sandoz.com or call: +1-609-422-4098Role RequirementsEssential Requirements:*Bachelor's degree in biochemistry, chemical engineering, bioengineering, or related technical field with 3+ years of lab related experience or Master's with a minimum 1 year lab related experience.*Previous experience with biotech/biopharmaceutical purification processes such as chromatographic separation, depth filtration, tangential flow filtration, adventitious viral clearance, or impurity clearance.*Demonstrate effective communication and collaboration skills*Strong organization, analytical, and problem-solving skills with attention to detailsDesired Requirements:*Knowledge in viral gene therapy and previous experience with viral vector process development is preferredWhy Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combiningto achieve breakthroughs that change patients' lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-cultureBenefits and Rewards: Read our handbook to learn about all the ways we'll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewardsCommitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $80,000-$120,000/year; however, while salary ranges are effective from 1/1/23 through 12/31/23, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an 'at-will position' and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn aboutsuitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/networkDivisionBiomedical ResearchBusiness UnitBIOLOGICS RESEARCH CENTERWork LocationSan Diego, CACompany/Legal EntityNIBRIFunctional AreaResearch & DevelopmentJob TypeFull TimeEmployment TypeRegularShift WorkNoEarly TalentYes#J-18808-Ljbffrby Jobble

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Research Scientist Novartis Jobs

Research Scientist Necropsyhistology Preclinical SafetyMay 1, 2024

Research Scientist Ii RdApril 28, 2024

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Research Scientist Necropsyhistology Preclinical Safety
May 1, 2024

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April 28, 2024

Research Scientist Ii Rd
April 23, 2024