Job Description: Job Title: Associate Research ScientistLocation: San Diego, CA*OnsiteTop Skills:- Bachelor's degree in a scientific discipline with 2-4 years work experience in the Pharma industry.Demonstrate proficiency with sterile cell culture, cell-based assays (CTG, apoptosis) and molecularbiology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR, Flow Cytometry)Experience with high-throughput drug screening is a plus.*Job Description:This Associate Research Scientist will join the Translational Development Group in San Diego. The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery. The individual will be responsible for the execution of defined experiments and data analysis. The position will require handling of tumor cell lines, blood samples, and patient-derived tissues. The associate will be expected to maintain an electronic lab notebook and organize results into reports or presentations. The ideal candidate will possess strong communication, presentation, writing, and record-keeping skills. The successful candidate will have a proven technical and scientific track record and experience working in a multi-disciplinary team environment.*Responsibilities will include, but are not limited to, the following:Semi-independently execute defined experiments, data analysis and data QCReport on scientific results to meet project deadlinesWork at the bench to develop and execute established and Client molecular and cell-based assays fordrug screening as well as understanding molecular pathways (Proliferation, Apoptosis, FlowCytometry etc.)Perform cell biology and molecular biology including primary and tumor cell culture, lentiviraltransductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, andELISA. Some training may be providedHands on experience in working with CRISPR, siRNA and shRNA is a plus. Training will be provided.May involve handling and processing patient derived tissues and blood samplesCollaborate effectively and cultivate positive and productive relationships with other scientistsMay involve presentation of data to manager and project teamThoughtful review of data and help plan next stepsParticipate in maintenance of routine laboratory instrumentation and suppliesAdherence to laboratory safety policies and practices*Qualifications:Have a Bachelor's degree in a scientific discipline with at least 2-4 years work experience in the Pharma industry. Masters degree acceptable. PhD candidates will not be considered.Demonstrate proficiency with sterile cell culture, cell-based assays (CTG, apoptosis) and molecularbiology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR, Flow Cytometry)Experience with high-throughput drug screening is a plusPossess some trouble shooting and problem-solving skills to resolve technical questions in a multi-disciplinary environment.Be able to work in fast paced environment with changing priorities.Possess excellent communication, organization skills and attention to detail.#J-18808-Ljbffrby Jobble

Job Description: Top Skills: •PhD with 2+ years of industry experience in molecular assay development, or MS/MA in Molecular Biology or similar with 5+ years of related experience, or BS/BA with 10+ years of related experience. •Design, develop, and qualify molecular-based analytical methods, including multiplex PCR-based assays using qPCR, RT-qPCR, ddPCR, to support pipeline cell therapies. •Experience designing and executing experiments to demonstrate assay comparability and to determine assay performance, including the assessment of specificity, accuracy, precision, linearity, and robustness. •Prepare complex technical documents, including SOPs, test methods, study protocols, and reports. Position Summary Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and Client's continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible. The Molecular Assay Development team is seeking an accomplished (Senior) Scientist to join our team within the Cellular Therapy Analytical Development (CTAD) organization. The (Senior) Scientist will act as a mentor and leader within a team of scientists who are collectively responsible for molecular biology-based QC and characterization methods supporting autologous and allogeneic cell therapies. These methods will be used to further the understanding of cell therapies, support development of the manufacturing processes, and QC release of the drug product. This position is responsible for the technology platform screening, development, qualification, and transfer of molecular biology-based analytical methods; as well as the life-cycle management of these methods. The (Senior) Scientist will have extensive hands-on experience in assay development; possess excellent communication skills; and be able to work with cross-functional teams in order to effectively transfer analytical methods, as wells as maintain and troubleshoot existing methods. Key Responsibilities •Design, develop, and qualify molecular-based analytical methods, including multiplex PCR-based assays using qPCR, RT-qPCR, ddPCR, to support pipeline cell therapies. •Provide leadership and mentorship within a team responsible for assessing new technology, developing molecular biology-based analytical methods, and managing method lifecycle. •Prepare complex technical documents, including SOPs, test methods, study protocols, and reports. •Ensure successful transfer of assays to quality control (QC) and commercial teams as needed. •Establish best practices for molecular biology-based methods by intended use and phase of testing •Develop strategies, lead studies, and implement changes to improve existing method performance in development and QC settings to support scalability and reduce resource burden. •Assist in investigations and troubleshoot molecular-biology based analytical methods by designing and overseeing studies and analyzing data sets with internal colleagues. •Present development updates and communicate with project leads, project teams, QC teams, operations teams, process development teams and other internal/external collaborators, as needed. •Analyze data and contribute to complex technical reports and team presentations. Qualifications & Experience •PhD with 2+ years of industry experience in molecular assay development, or MS/MA in Molecular Biology or similar with 5+ years of related experience, or BS/BA with 10+ years of related experience. •Expert knowledge of and hands-on experience developing and optimizing analytical methods using molecular biology techniques, including various PCR-based methods and/or next-generation sequencing. •Experience designing and executing experiments to demonstrate assay comparability and to determine assay performance, including the assessment of specificity, accuracy, precision, linearity, and robustness. •Expert experience writing technical documents, including test methods, SOPs, study protocols, and study reports. •Track record of successful transfer and management of analytical methods. •Ability to work effectively and efficiently as a team player in a dynamic environment. •Strong problem-solving ability in order to troubleshoot complex technical and scientific problems. •Exceptional attention to detail, strong organizational skills, and a demonstrated ability to complete projects within a timeline. •Effective communicator

Job Description: Job Title: Associate Research Scientist Location: San Diego, CA*Onsite Top Skills: - Bachelor's degree in a scientific discipline with 2-4 years work experience in the Pharma industry. •Demonstrate proficiency with sterile cell culture, cell-based assays (CTG, apoptosis) and molecular biology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR, Flow Cytometry) •Experience with high-throughput drug screening is a plus. *Job Description: This Associate Research Scientist will join the Translational Development Group in San Diego. The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery. The individual will be responsible for the execution of defined experiments and data analysis. The position will require handling of tumor cell lines, blood samples, and patient-derived tissues. The associate will be expected to maintain an electronic lab notebook and organize results into reports or presentations. The ideal candidate will possess strong communication, presentation, writing, and record-keeping skills. The successful candidate will have a proven technical and scientific track record and experience working in a multi-disciplinary team environment. *Responsibilities will include, but are not limited to, the following: •Semi-independently execute defined experiments, data analysis and data QC •Report on scientific results to meet project deadlines •Work at the bench to develop and execute established and Client molecular and cell-based assays for drug screening as well as understanding molecular pathways (Proliferation, Apoptosis, Flow Cytometry etc.) •Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and ELISA. Some training may be provided •Hands on experience in working with CRISPR, siRNA and shRNA is a plus. Training will be provided. •May involve handling and processing patient derived tissues and blood samples •Collaborate effectively and cultivate positive and productive relationships with other scientists •May involve presentation of data to manager and project team •Thoughtful review of data and help plan next steps •Participate in maintenance of routine laboratory instrumentation and supplies •Adherence to laboratory safety policies and practices *Qualifications: •Have a Bachelor's degree in a scientific discipline with at least 2-4 years work experience in the Pharma industry. Masters degree acceptable. PhD candidates will not be considered. •Demonstrate proficiency with sterile cell culture, cell-based assays (CTG, apoptosis) and molecular biology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR, Flow Cytometry) •Experience with high-throughput drug screening is a plus •Possess some trouble shooting and problem-solving skills to resolve technical questions in a multi- disciplinary environment. •Be able to work in fast paced environment with changing priorities. •Possess excellent communication, organization skills and attention to detail.

Research Scientist Honorvet Technologies Jobs

Scientific Associate Research Scientist
April 28, 2024

Scientific Research Scientist
April 22, 2024

Scientific Associate Research Scientist
April 18, 2024

Scientific Associate Research Scientist
April 4, 2024

Quick filters

Top companies

Research Scientist Honorvet Technologies Jobs

Scientific Associate Research ScientistApril 28, 2024

Scientific Research ScientistApril 22, 2024

Scientific Associate Research ScientistApril 18, 2024