The University of Texas MD Anderson Cancer Center in Houston is one of the world's most respected centers focused on cancer patient care, research, education, and prevention. It was named the nation's No. 1 hospital for cancer care in U.S. News & World Report's 2022-2023 rankings. It is one of the nation's original three comprehensive cancer centers designated by the National Cancer Institute.

The purpose of the Research Scientist position is to apply technical expertise and experience to plan, coordinate, design, supervise and carry out research projects. The primary purpose of the Research Scientist is to fully participate in cutting-edge science and applying analytical expertise and experience to plan, coordinate, design and carry out research project(s). We are seeking a highly motivated enthusiastic person to perform scRNASeq and Spatial Transcriptomics assays as well as willing to learn new technologies and participates in developing new platforms.

The ideal candidate will have a background in Molecular Biology Techniques and Next Generation Sequencing (NGS).

KEY FUNCTIONS

Participate in scientific research projects:

A. Technical Competencies

* Independently perform all aspects of the experiments, which may include, NA Extraction and QC, Library Preps, Hybridization/Capture, and sequencing.

* Independently perform scRNASeq and Spatial Transcriptomics techniques.

* Prepare nucleic acid QC reports & sequencing coverage summaries and submit for manager review.

* Under the supervision of the Laboratory manager, evaluate new techniques/reagents and learning new skills to enhance research efforts.

* Use LIMS system (MOCLIA) and generate multiple reports as needed.

* Participate in laboratory automation.

* Plan and train other laboratory personnel on new laboratory techniques, the use of laboratory equipment, and safety procedures.

* Monitor and anticipate laboratory inventory in terms of equipment and supplies.

* Maintain good, detailed experimental records, evaluate resulting research data, and present findings.

* Prepare scientific documents for publication.

* Responsible for overall laboratory safety to pass yearly laboratory safety inspection by MDACC Environmental Health and Safety.

* Attends weekly lab meetings and take notes.

* Work closely and maintain good working relationship with other staff members.

* Other duties as assigned.

B. Data Analysis Competencies:

* Perform sequencing data de-multiplexing and generating the fastq and bam files.

* Perform TMB, CNVs, MSI analysis.

* Generate and review sequencing QC metrics.

* Perform scRNASeq data analysis and generate web summaries.

* Help in evaluating/validating new NGS platforms by assessing their data accuracy, precision and LODs.

* Perform other correlative studies as needed.

Working Conditions

This position requires :

Yes

No

Working in Office Environment

X

Working in Patient Care Unit (e.g. Nursing unit; outpatient clinic)

X

Exposure to human/animal blood, body fluids, or tissues

X

Exposure to harmful chemicals

X

Exposure to radiation

X

Physical Demands

Indicate the time required to do each of the following physical demands:

Time Spent

Never

0%

Occasionally

1-33%

Frequently

34-66%

Continuously

67-100%

Standing

X

Walking

X

Sitting

X

Reaching

X

Lifting/Carrying

Up to 10 lbs.

X

10lbs to 50 lbs.

X

More than 50 lbs.

X

Pushing/Pulling

Up to 10 lbs.

X

10lbs to 50 lbs.

X

More than 50 lbs.

X

Use computer/keyboard

X

EDUCATION

Required: Master's degree in one of the natural sciences or related field.

Preferred: PhD in one of the natural sciences or Medical degree.

EXPERIENCE

Require: Four years of experience in experimental or scientific work. With PhD, no experience required. With Medical degree, two years of experience in experimental or scientific work.

Preferred: Five years of related experience to include research work at MDACC. Ideal candidate will have a background in Molecular Biology Techniques and Next Generation Sequencing (NGS).

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

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